| State | HIDTA | HIDTA Counties | Number of Counties |
| Alabama | Gulf Coast HIDTA | Baldwin, Jefferson, Madison, Mobile, Montgomery, Morgan | 6 |
| Arizona | SW Border-AZ Region | Cochise, La Paz, Maricopa, Mohave, Pima, Pinal, Santa Cruz, Yuma | 8 |
| California | Los Angeles HIDTA | Los Angeles (City of Los Angeles), Orange, Riverside, San Bernardino | 4 |
| Central Valley California HIDTA | Fresno, Kern, Kings, Madera, Merced, Sacramento, San Joaquin, Stanislaus, Tulare | 9 | |
| Northern California HIDTA | Alameda, Contra Costa, Lake, Marin, Monterey, San Francisco, San Mateo, Santa Clara, Santa Cruz, Sonoma | 10 | |
| SW Border-CA Region | Imperial, San Diego | 2 | |
| Colorado | Rocky Mountain HIDTA | Adams, Arapahoe, Boulder, Denver, Douglas, Eagle, El Paso, Garfield, Grand, Jefferson, La Plata, Larimer, Mesa, Moffat, Pueblo, Routt, Weld | 17 |
| Connecticut | New England HIDTA | Fairfield, Hartford, New Haven | 3 |
| Florida | Central FL HIDTA | Hillsborough, Orange, Osceola, Pinellas, Polk, Seminole, Volusia | 7 |
| North Florida HIDTA | Alachua, Baker, Clay, Columbia, Duval, Nassau, Putnam, Flagler, St. Johns and Marion | 10 | |
| South Florida HIDTA | Broward, Dade, Monroe, (City of Miami), Palm Beach | 4 | |
| Georgia | Atlanta HIDTA | Barrow, Bartow, Cherokee, Clayton, Douglas, Fayette, Forsyth, and Henry | 8 |
| Hawaii | Hawaii HIDTA | City and County of Hawaii (the Islands of Hawaii and Oahu), Honolulu, Kauai County (the Island of Kauai), Maui County (the Islands of Maui, Molokai and Lanai) | 4 |
| Illinois | Chicago HIDTA | Cook, (City of Chicago), Grundy, Kendall, Will | 4 |
| Indiana | Lake County HIDTA | Lake | 1 |
| Iowa | Midwest HIDTA | Appanoose, Black Hawk, Linn, Marshall, Muscatine, Polk, Pottawattamie, Scott, Woodbury | 9 |
| Kansas | Midwest HIDTA | Barton, Cherokee, Crawford, Finney, Franklin, Johnson, Labette, Leavenworth, Miami, Saline, Sedgwick, Seward, Shawnee, Wyandotte | 14 |
| Kentucky | Appalachia HIDTA | Adair, Bell, Breathitt, Clay, Clinton, Cumberland, Floyd, Harlan, Jackson, Knott, Knox, Laurel, Lee, Leslie, McCreary, Magoffin, Marion, Monroe, Owsley, Perry, Pike, Pulaski, Rockcastle, Taylor, Warren, Wayne, Whitley | 27 |
| Louisiana | Gulf Coast HIDTA | Bossier, Caddo, Calcasieu, East Baton Rouge, Jefferson, Lafayette, Orleans and Ouachita Parishes | 8 |
| Maine | New England HIDTA | Cumberland | 1 |
| Maryland | Wash/Baltimore HIDTA | Anne Arundel, Baltimore, Charles, Howard, Montgomery, Prince GeorgeŐs (City of Baltimore) | 6 |
| Massachusetts | New England HIDTA | Essex, Hampden, Middlesex, Plymouth, Suffolk, Worcester | 6 |
| Michigan | Michigan HIDTA | Allegan, Genesee, Kalamazoo, Kent, Macomb, Oakland, Van Buren, Washtenaw, Wayne | 9 |
| Mississippi | Gulf Coast HIDTA | Hancock, Harrison, Hinds, Jackson, Lafayette, Madison, Rankin | 7 |
| Missouri | Midwest HIDTA | Benton, Boone, Buchanan, Cape Girardeau, Christian, Clay, Cole, Franklin, Greene, Jasper, Jackson, Jefferson, Lafayette, Lawrence, Marion, Platte, Ray, Scott, St. Charles, Texas, St. Louis(City of St Louis) | 21 |
| Montana | Rocky Mountain HIDTA | Cascade, Flathead, Lewis and Clark, Missoula, Yellowstone | 5 |
| Nebraska | Midwest HIDTA | Dakota, Dawson, Dodge, Douglas, Gage, Hall, Jefferson, Lancaster, Madison, Platte, Sarpy, ScottŐs Bluff | 12 |
| Nevada | Nevada HIDTA | Clark, Washoe | 2 |
| New Hampshire | New England HIDTA | Hillsborough | 1 |
| New Jersey | NY/NJ HIDTA | Bergen, Essex, Hudson, Passaic, Union | 5 |
| Philly/Camden HIDTA | Camden, (City of Camden) | 1 | |
| New Mexico | SW Border-NM Region | Bernalillo, Chaves, Dona Ana, Eddy, Grant, Hidalgo, Lea, Lincoln, Luna, Otero, Rio Arriba, Sandova, Santa Fe, San Juan, Torrance, Valencia | 16 |
| New York | NY/NJ HIDTA | Nassau, Suffolk, Westchester, (New York City: Bronx, Brooklyn, New York, Richmond and Queens Counties) | 8 |
| North Carolin | Atlanta HIDTA | HIDTADurham, Johnston, Wake, Wayne, and Wilson | 5 |
| North Dakota | Midwest HIDTA | Burleigh, Cass, Grand Forks, Morton, Ramsey, Richland, Walsh, Ward | 8 |
| Ohio | Ohio HIDTA | Cuyahoga, Fairfield, Franklin, Greene, Hamilton, Lucas, Mahoning, Montgomery, Stark, Summit, Warren | 11 |
| Oklahoma | North Texas HIDTA | Cleveland, Comanche, Muskogee, Oklahoma, Sequoyah, Tulsa | 6 |
| Oregon | Oregon HIDTA | Clackamas, Deschutes, Douglas, Jackson, Marion, Multnomah, Umatilla, Washington | 8 |
| Pennsylvania | Philly/Camden HIDTA | Philadelphia (City of Philadelphia) | 1 |
| Rhode Island | New England HIDTA | Providence | 1 |
| South Dakota | Midwest HIDTA | Beadle, Brookings, Brown, Clay, Codington, Custer, Fall River, Lawrence, Lincoln, Meade, Minnehaha, Pennington, Union, Yankton | 14 |
| Tennessee | Appalachia HIDTA | Bledsoe, Campbell, Claiborne, Clay, Cocke, Cumberland, Fentress, Franklin, Grainger, Greene, Grundy, Hamblen, Hancock, Hawkins, Jackson, Jefferson, Knox, Macon, Marion, Overton, Pickett, Putnam, Rhea, Scott, Sequatchie, Sevier, Unicoi, Van Buren, White | 29 |
| Texas | Houston HIDTA | Aransas, Brooks, Fort Bend, Galveston, Hardin, Harris, Jefferson, Jim Wells, Kennedy, Kleberg, Liberty, Nueces, Orange, Refugio, San Patricio, Victoria, (City of Houston) | 16 |
| North TX HIDTA | Collin, Dallas, Denton, Ellis, Henderson, Hood, Hunt, Johnson, Kaufman, Lubbock, Navarro, Parker, Rockwall, Smith, Tarrant, (Cities of Dallas and Fort Worth) | 15 | |
| SW Border-S TX Region | Bexar, Cameron, Dimmit, Hidalgo, Jim Hogg, Kinney, La Salle, Maverick, Starr, Val Verde, Webb, Willacy, Zapata, Zavala | 14 | |
| SW Border-W TX Region | Brewster, Crockett, Culberson, Jeff Davis, El Paso, Hudspeth, Pecos, Presidio, Reeves, Terrell | 10 | |
| Utah | Rocky Mountain HIDTA | Davis, Salt Lake, Summit, Utah, Washington, Weber | 6 |
| Vermont | New England HIDTA | Chittenden | 1 |
| Virginia | Wash/Baltimore HIDTA | Arlington, Chesterfield, Fairfax, Loudon, Hanover, Henricho, Prince George, Prince William, (City of Alexandria and City of Richmond) | 8 |
| Washington | Northwest HIDTA | Benton, Clark, Cowlitz, Franklin, King, Kitsap, Lewis, Pierce, Skagit, Snohomish, Spokane, Thurston, Whatcom, Yakima | 14 |
| West Virginia | Appalachia HIDTA | Boone, Braxton, Cabell, Gilmer, Kanawha, Lewis, Lincoln, Logan, Mason, McDowell, Mingo, Wayne | 12 |
| Wisconsin | Milwaukee HIDTA | Kenosha, Milwaukee, Racine, Waukesha | 4 |
| Wyoming | Rocky Mountain HIDTA | Albany, Campbell, Laramie, Natrona, Sweetwater, Uinta | 6 |
| Wash., D.C. | Wash/Baltimore HIDTA | District of Columbia | 0 |
| Puerto Rico | PR/VI HIDTA | Territory of Puerto Rico | 0 |
| Virgin Islands | PR/VI HIDTA | Territory of U.S. Virgin Islands | 0 |